Work on blood flow calibration published

A work that aimed to calibrate blood flow - as measured by diffuse correlation spectroscopy (DCS) has just been accepted for publication in Neurophotonics. This work was developed at the University of Pennsylvania in collaboration with our lab and the group at Western University in Canada.

Blood flow measured by DCS has physical units, of $$cm^2/s$$. However, physicians are used to report blood flow in units of ml of blood/100g/min. In this work, we employed an invasive optical technique with simultaneous DCS to find a calibration factor for the latter. This factor was later tested in an independent dataset, showing its robustness to the experimental protocol (if the measurements configuration was kept the same).

The work, entitled "Noninvasive continuous optical monitoring of absolute cerebral blood flow in critically ill adults," by Lian He et al., can be accessed on https://www.spiedigitallibrary.org/journals/neurophotonics/volume-5/issue-04/045006/Noninvasive-continuous-optical-monitoring-of-absolute-cerebral-blood-flow-in/10.1117/1.NPh.5.4.045006.full?SSO=1

#lobunicamp #fnirs #dcs #collaboration